Oct 16 2008
We have been fortunate to gain a new and very skilled employee in Singapore, Mr Henry Wang, which means that we now have a native Chinese speaker in CLC bio. In this video Henry uses his mother tongue to explains how to assemble data from two different NGS platforms, Illumina Genome Analyzer and 454, in one run. The data set contains both paired-ends and single reads.
Oct 09 2008
CLC bio announced today an agreement with the J. Craig Venter Institute, a not-for profit genomic-focused research institute. The accord consists of a multi-year site license for the entire CLC bio bioinformatics suite of products. The goal is to implement CLC bio’s enterprise solution as a scientific platform across all JCVI sites. This enterprise solution will provide different research projects at JCVI with a coherent integration layer and a standardized way of developing custom software and specialized algorithms.
According to Granger Sutton, Senior Director of Informatics at JCVI
JCVI will benefit from implementing this enterprise solution, as it is a full enterprise platform that integrates, supports, and enhances workflows across different technologies and geographical sites. CLC bio’s software platform impressed our evaluators with its advanced features and intuitive, user-friendly interface.
CLC bio’s North America CEO Jan Lomholdt states
We’re proud to announce this strategic partnership with JCVI, a leader in genomic research. This site license agreement represents another stamp of approval of CLC bio’s solutions by a globally recognized institution in the scientific community. This partnership will lead to magnificent accomplishments in the scientific arena.
The enterprise solution CLC bio will be implementing at JCVI contains both server structure and support for all major database formats. This ensures a smart and efficient solution for sharing centralized bioinformatics data in a client/server architecture, where the server contains one or more databases and the clients are CLC bio’s workbenches.
CLC Bio’s solution is a technological gateway that efficiently accesses all data and analysis in a single platform. With CLC bio’s enterprise solution all proprietary algorithms and solutions developed at JCVI can be accessed from the same bioinformatics platform, ensuring a streamlined workflow with minimal overhead and no tedious time-wasting procedures. CLC bio’s developer kit will enable JCVI to build targeted plug-ins for their internal use, while allowing JCVI to interact based on the same platform with worldwide collaborators.
Oct 06 2008
Today, a new company emerged as a player in high throughput DNA sequencing.
Complete Genomics of California has emerged from what they themselves call “stealth mode” with the promise of releasing a platform that will sequence a human genome for 5000$ already next year.
Their sequencing platform is based on DNA nano balls and sequencing by hybridization.
George Church is on the scientific advisory board, which may explain some of the statements me made recently about a sharp drop in sequencing costs.
Oct 03 2008
Following an overwhelming reception of CLC Genomics Workbench 1.0, CLC bio is happy to announce the release of its next major version of their flagship product: CLC Genomics Workbench 2.0. Additionally, CLC bio has taken another important step in leading next generation sequencing data analysis by becoming an Illumina Connect partner. Illumina Connect is a bioinformatics software partnership program established by Illumina, Inc. to advance data integration and analysis.
Jordan Stockton, Marketing Manager for Computational Biology at Illumina states
CLC Genomics Workbench 2.0 provides scientists using Illumina’s Genome Analyzer with advanced downstream analysis. Not only is it fast, but the new version of CLC Genomics Workbench offers alignment and assembly functionality that previously required larger investments in computer hardware. With its intuitive graphical interface, this application provides a simple desktop solution to biologists who might otherwise require the assistance of a dedicated bioinformatics professional.
As an Illumina Connect partner, CLC bio has access to information in the ongoing development of Next Generation Sequencing tools, ensuring that CLC bio’s solutions will be able to fully support Illumina’s tools, including new releases.
Director of Scientific Software Solutions at CLC bio, Dr. Roald Forsberg states
This release is inspired by the great advances in human genetics that are being powered by Next Generation Sequencing technologies, like Illumina. Large scale projects like the Cancer Genome Project and the 1000 Genomes Project are creating a vast amount of data that will transform biomedical research. However, before the revolution in human genetics can be fully realized by the research community there is a dramatic need for bioinformatics solutions that will allow biomedical researchers to handle and analyze sequencing projects at the human genomics scale - something we aim to solve with this and upcoming releases.
CLC Genomics Workbench 2.0 will include several prominent new features, among these:
CLC Genomics Workbench is the first and only comprehensive analysis package which can analyze and visualize data from all major NGS platforms, such as Illumina’s Genome Analyzer, SOLiD by Applied Biosystems, 454 GS flx by Roche, and HeliScope by Helicos. CLC Genomics Workbench is platform independent, running on Mac OS X, Windows, and Linux - including 64bit versions.
To read more about CLC Genomics Workbench go to: www.clcbio.com/genomics
http://www.clcbio.com/index.php?id=17
Thomas Knudsen, CEO
Phone: +45 70 22 55 09
E-mail: info@clcbio.com
Oct 01 2008
Just as economists have a Big Mac index to rate the cost of living in different countries, scientists in genomics are using the full human genome sequencing cost as an index of how much DNA sequencing costs. Judging by this index October seems to be a good month for sequencing customers.
Last month, several sources - including the Genetic Genealogist - quoted George Church for claiming that the cost of sequencing a human genome would drop to 5000$ in October 2008.
Today, Applied Biosystems posted a press release about their new SOLiD 3 system which is expected to enable scientists to sequence a human genome for approximately $10,000.
Earlier this year, AB claimed that they had used the SOLiD system to sequence a human genome for less than $60,000. Now, technical enhancements to the new platform that enable higher sample and data throughput are expected to further decrease the cost of genomic sequencing.
Church also recently predicted a 1000$ genome already by the end of next year and with AB recent release and Illuminas predicted capacity increase this goal suddently seems within reach.
However, October has only just started and we may still be in for more exiting news!
