Feb 07
White paper on de novo assembly in CLC Assembly Cell 4.0
We are continuously developing the CLC de novo assembly algorithm and our new assembler is an improvement over previous versions with better support for large data sets and integrated scaffolding for joining contigs based on paired reads information.
The white paper on our new de novo assembler includes some brand new performance benchmarks on genome assembly of E. Coli, A. thaliana and Homo sapiens, respectively.
The results demonstrate the assembler’s ability to produce accurate assemblies extremely fast using both standard consumer hardware and server systems. For example, the assembly of a high coverage dataset for the A. thaliana genome is completed in just half an hour on a quad-core laptop, while an assembly of the human genome using a 43x coverage dataset takes just seven hours on a quad-processor system.